ea0056oc11.1 | Clinical practice in endocrine tumours: combining conventional and molecular features | ECE2018
Lippert Juliane
, Appenzeller Silke
, Liang Raimunde
, Sbiera Silviu
, Kircher Stefan
, Altieri Barbara
, Nanda Indrajit
, Weigand Isabel
, Gehrig Andrea
, Steinhauer Sonja
, Mueller Clemens
, Kroiss Matthias
, Rost Simone
, Rosenwald Andreas
, Fassnacht Martin
, Ronchi Cristina
Adrenocortical carcinoma (ACC) has heterogeneous prognosis and no effective targeted therapies. Pan-genomic studies identified complex molecular patterns related to outcome. Our study aimed at identification of an easy-to-apply molecular signature for better personalized prognostic stratification. A total of 107 ACC patients were enrolled. Clinical/histopathological parameters of prognostic relevance were evaluated. Targeted molecular analysis was performed on DNA ...